09/25/2026
Colorado's natural medicine program's updated rules and fee schedule introduce several changes businesses should plan for now:
→ Owner Entity License: Companies serving as natural medicine business owners now have their own license type ($1,000 application fee, $3,000 compliance fee). At least one owner must still be a licensed individual.
→ Limited Regulated Natural Medicine Sales License: Created under HB 26-1325, this license lets Healing Center Owners sell natural medicine to participants. Healing Centers can now sell only through a co-located sales licensee, and sales must happen immediately before an administration session.
→ Private residence Healing Centers: Now allowed if the space is a separate, securely accessible, unoccupied structure, local zoning permits it and all other Healing Center requirements are met.
→ Higher renewal fees: Most license types see increases of $250 to $3,000, effective December 31, 2026.
The rules also update inventory-tracking, transport, and recordkeeping requirements and expressly prohibit personal use and non-regulated natural medicine on licensed premises.
Key dates:
- July 1, 2026: Final rules took effect
- August 12, 2026: New fee schedule and sales license took effect
- December 31, 2026: Higher renewal fees begin
- This fall: Permanent rulemaking expected on the sales license
Read the full breakdown from Barine Majewska, Juliana Todeschi, Colleen Mitchell and Emily Schroder: https://vicentellp.com/insights/2026-colorado-natural-medicine-rule-changes-what-licensees-need-to-know/
Colorado's new natural medicine rules create an Owner Entity License and a limited sales license, open the door to private residence Healing Centers and raise most renewal fees. Here's what licensees need to know.