01/03/2019
NEW FDA BLACK BOXED WARNING ABOUT AMPUTATION RISK
The Food and Drug and Administration (FDA) issued a black boxed warning, the most serious type of warning the FDA issues, for users of the highly prescribed type 2 diabetes drug, Invokana.
After clinical trials were completed, the FDA confirmed that Invokana and Invokamet (canagliflozin) caused an increased risk of leg and foot amputations in patients. Invokamet is similar to Invokana, but it contains metformin, another drug used in the treatment of type 2 diabetes, whereas Invokana only contains canagliflozin.
There is some indication that the vaccination is linked to death. NCIV analysis indicates that there were more than 1,100 serious adverse events reports made to the Vaccine Adverse Events Reporting System from 1990 until September 2015 related to shingles-containing vaccinations. Of these reports, 90 were for deaths associated with the shingles vaccine.
Both chickenpox and shingles may result in serious damage to the nervous system including conditions like meningitis, encephalitis, acute disseminated encephalomyelitis (ADEM) and stroke. Some people who develop shingles have serious side effects, such as Guillain-Barre syndrome, congestive heart failure, or varicella pneumonia.